Neurological

Dementia & Alzheimer's: Diagnosis Guide

Dementia affects memory, thinking, and daily function. While most causes aren't reversible, thorough investigation can identify treatable contributing factors and enable early support.

Most common type
Alzheimer's disease (60-70%)
UK prevalence
~1 in 14 over 65
Key initial test
Cognitive screening (MMSE/MoCA)
Blood tests
Rule out reversible causes

Early Warning Signs

Blood Tests to Rule Out Reversible Causes

TestRules Out
FBCAnaemia
TSHHypothyroidism — a treatable cause of cognitive decline
Vitamin B12 + folateDeficiency causing reversible cognitive impairment
CalciumHypercalcaemia can cause confusion
Liver function testsLiver disease affecting brain function (encephalopathy)
Kidney functionUraemia affecting cognition
HbA1c/glucoseDiabetes — poor control can affect cognition
Syphilis serologyRare but treatable cause if risk factors present

Types of Dementia

TypeKey Features
Alzheimer's diseaseGradual memory decline, most common type
Vascular dementiaStep-wise decline, often after strokes; linked to cardiovascular risk factors
Lewy body dementiaVisual hallucinations, fluctuating cognition, parkinsonism
Frontotemporal dementiaPersonality and behaviour changes, often younger onset
Early Diagnosis Enables PlanningWhile treatment options for progressive dementia remain limited, early diagnosis allows time for legal and financial planning (power of attorney, advance directives), access to support services, and in some cases, newer disease-modifying treatments for early Alzheimer's.
Is memory loss always dementia?
No — normal ageing causes some memory changes (occasionally forgetting names, needing more time to learn new things), but this doesn't significantly impair daily function. Dementia involves progressive decline that does affect independence.
Can dementia be prevented?
While not entirely preventable, managing cardiovascular risk factors (blood pressure, cholesterol, diabetes), staying physically and mentally active, maintaining social connections, and treating hearing loss are associated with reduced dementia risk.
Are new Alzheimer's drugs available?
Newer disease-modifying treatments (like lecanemab) targeting amyloid protein have shown modest benefit in slowing early Alzheimer's progression, though availability, cost, and side effect profiles vary by country and are still being established.
Medical Disclaimer: This page is for general education only and does not replace professional medical advice. Always consult a qualified healthcare provider.