Neurological Condition

Sciatica — Symptoms, Causes & When to Investigate

What causes sciatica, how to recognise red flag symptoms, and when tests beyond basic clinical assessment are needed.

Nerve involved
Sciatic nerve (L4–S1)
Most common cause
Lumbar disc herniation
Usually improves in
4–12 weeks

What Is Sciatica?

Sciatica is pain that travels along the path of the sciatic nerve — from the lower back through the hip and buttock and down the leg, usually one side only. It's caused by irritation or compression of the sciatic nerve roots.

Symptoms

Common Causes

Red Flag Symptoms — Urgent Referral:Loss of bladder or bowel control | Saddle anaesthesia (numbness around the groin/inner thighs) | Progressive neurological weakness | Sciatica with fever and back pain (possible spinal infection).

When Blood Tests Are Ordered

TestPurpose
ESR & CRPElevated if spinal infection or malignancy suspected
Full Blood CountAnaemia or infection
PSA (men)Prostate cancer as a cause of nerve compression
Calcium, ALPBone metastases
Blood glucoseDiabetic neuropathy as differential diagnosis

FAQs

Does sciatica always need MRI?
No — most cases (80–90%) resolve within 12 weeks without imaging. MRI is reserved for persistent symptoms, red flags, or if surgery is being considered.
What is the best treatment for sciatica?
Staying active (avoid bed rest). NSAIDs for pain. Physiotherapy and targeted exercises. Steroid injections for severe cases. Surgery (microdiscectomy) if neurological deficits progress or persist.
Is heat or ice better for sciatica?
Both can help — ice for acute pain (first 48–72 hours), heat for muscle spasm. Alternate as preferred.
Medical Disclaimer: Sciatica with bladder/bowel changes or bilateral leg weakness is a medical emergency (cauda equina syndrome) requiring immediate hospital assessment.