Preventive Health

Essential Health Checks in Your 40s

Your 40s are the decade when silent health conditions begin to emerge. These are the blood tests and screenings that can catch problems before they become serious.

NHS Health Check
Ages 40–74 (every 5 years)
Most important screens
BP, cholesterol, glucose, BMI
Cancer screens start
50 (bowel), 50–70 (breast)
Risk calculation
QRISK3 — 10-year CVD risk

The NHS Health Check (UK) / Equivalent (US/AU)

The NHS offers a free health check every 5 years for adults aged 40–74. It assesses your risk of heart disease, stroke, diabetes, kidney disease, and dementia.

What's CheckedWhy
Blood pressure#1 modifiable risk factor for stroke and heart disease
Total cholesterol + HDLCardiovascular risk assessment
Blood glucose or HbA1cType 2 diabetes or pre-diabetes
BMIObesity-related disease risk
Waist circumferenceCentral obesity — stronger CVD predictor than BMI
Smoking and alcoholLifestyle risk factors
Family historyHereditary conditions

Recommended Blood Tests in Your 40s

TestFrequencyWhy It Matters in Your 40s
Lipid profile (cholesterol)Every 5 years (or annually if elevated)LDL rises from 40s; early statin can prevent events
HbA1c / fasting glucoseEvery 3 years (or annually if pre-diabetic)Type 2 diabetes peaks in 40s–50s
Thyroid (TSH)Every 5 years (especially women)Thyroid disease common in women from 40s
FBC + iron (women)Every 3 yearsPre-menopausal iron loss + perimenopause transition
Vitamin DEvery 2–3 yearsDeficiency increasingly common
Blood pressureEvery yearSilent hypertension from 40s
QRISK3Your GP calculates your 10-year cardiovascular risk using QRISK3. If risk is ≥10%, lifestyle advice is given. If ≥10% with trial of lifestyle for 3 months, statins are offered. Ask for your QRISK3 score at your health check.

Cancer Screenings Starting in Your 40s–50s

CancerScreeningAge (UK)
Bowel cancerBowel scope (sigmoidoscopy) once55 (UK); faecal immunochemical test 50–74
Breast cancer (women)Mammogram every 3 years50–71 in UK (extension to 47–73 planned)
Cervical (women)Smear every 3 years25–49 (every 5 years from 50)
Aortic aneurysm (men)Abdominal ultrasound once65
What is pre-diabetes and should I be worried?
Pre-diabetes (HbA1c 42–47 mmol/mol; fasting glucose 6.1–6.9 mmol/L) means blood sugar is above normal but not yet diabetic. With lifestyle changes, 50% of people with pre-diabetes avoid developing type 2 diabetes.
How do I know if I have high blood pressure?
High blood pressure has NO symptoms until very advanced. A single reading >140/90 warrants monitoring. Diagnosis requires sustained readings over 3 months or a high one-off reading (>180/120).
Should I check my heart privately?
A coronary calcium score (CAC) CT scan is a private test that directly shows calcium deposits in heart arteries — the most accurate predictor of future heart attack. Worth considering if QRISK3 is borderline and you want more certainty.
Medical Disclaimer: This page is for general education only and does not replace professional medical advice. Always consult a qualified healthcare provider.