When to Worry

Mole Checks: The ABCDE Rule for Melanoma

Skin cancer, including melanoma, is highly treatable when caught early. Learning to check your own skin using the ABCDE rule could save your life.

ABCDE stands for
Asymmetry Border Colour Diameter Evolving
2-week wait referral
For suspicious lesions
5-year survival (early melanoma)
~99%
5-year survival (late melanoma)
~30%

The ABCDE Rule for Checking Moles

LetterWhat to Look For
A — AsymmetryOne half doesn't match the other
B — BorderIrregular, notched, or blurred edges
C — ColourUneven colour; multiple shades of brown, black, red, or blue
D — DiameterLarger than 6mm (about the size of a pencil eraser) — though melanomas can be smaller
E — EvolvingChanging in size, shape, colour, or symptoms (itching, bleeding) over time

Other Warning Signs

Risk Factors for Skin Cancer

Suspicious Mole — Get Checked UrgentlyAny mole meeting the ABCDE criteria, especially rapid changes or bleeding, warrants an urgent GP appointment. In the UK, GPs can refer suspicious lesions on a 'two-week wait' urgent pathway for rapid dermatology assessment.
Monthly Self-ChecksCheck your entire skin monthly, including your back, scalp, soles of feet, and between toes (use a mirror or ask a partner for help with hard-to-see areas). Take photos of moles you're monitoring to track changes over time.
Are all new moles dangerous?
No — new moles commonly appear up until around age 40, especially with sun exposure. However, new moles appearing after 40, or any mole showing ABCDE features, should be checked.
What happens at a mole check appointment?
A doctor examines the lesion, often with a dermatoscope (magnifying light tool). Suspicious lesions are usually removed (excision biopsy) for laboratory analysis to confirm or rule out cancer.
Can melanoma occur in areas without sun exposure?
Yes — melanoma can occur on the soles of feet, palms, under nails, and even in the eye, particularly in people with darker skin tones, where it's often diagnosed later due to lower awareness of these sites.
Medical Disclaimer: This page is for general education only and does not replace professional medical advice. Always consult a qualified healthcare provider.