Test Comparison
| Test | Accuracy | Notes |
|---|---|---|
| Urea breath test | Very accurate (95%+) | Preferred for initial diagnosis and confirming eradication |
| Stool antigen test | Very accurate (95%+) | Good alternative, especially for children |
| Blood antibody test | Confirms past exposure, not current infection | Antibodies persist even after successful treatment — not useful for confirming cure |
| Endoscopy with biopsy | Very accurate | Used when endoscopy is needed anyway for other reasons |
Important Testing Preparation
- Stop PPIs (omeprazole, lansoprazole) for at least 2 weeks before breath/stool testing — otherwise false negative results are common
- Stop antibiotics for at least 4 weeks before testing
- Testing too soon after treatment can give false results
Test to Confirm EradicationAfter H. pylori treatment, a follow-up breath or stool test (at least 4 weeks after finishing antibiotics and 2 weeks off PPIs) confirms successful eradication — this is especially important if you had a peptic ulcer.
Should everyone with indigestion be tested for H. pylori?
Testing is generally recommended for those with peptic ulcer symptoms, or persistent indigestion not responding to simple measures, particularly before starting long-term acid suppression.
Can H. pylori cause cancer?
Chronic H. pylori infection is a recognised risk factor for stomach cancer and MALT lymphoma, which is part of why eradication is recommended when infection is found.
Medical Disclaimer: This page is for general education only and does not replace professional medical advice. Always consult a qualified healthcare provider.