What Is Vitamin B6?
Vitamin B6 (pyridoxine) supports brain development, nerve function, immune health and the production of haemoglobin and neurotransmitters like serotonin.
Normal Vitamin B6 Range
| Test | Normal Range |
|---|---|
| Pyridoxal 5-phosphate (active B6) | 5–50 ng/mL |
Symptoms of Deficiency
- Fatigue and irritability
- Cracked or sore lips and mouth ulcers
- Tingling or numbness in hands and feet
- Confusion and depressed mood
- Anaemia
- Skin rashes (dermatitis)
Who Is at Risk of Deficiency?
- People with kidney disease
- Heavy alcohol users
- Autoimmune conditions
- Those on certain medications (e.g. isoniazid, some seizure drugs)
- Pregnant women
Vitamin B6 Toxicity
Very high doses from long-term high-dose supplements (rarely from food) can cause nerve damage, numbness and difficulty walking — always stay within recommended supplement limits.
Important: Discuss abnormal vitamin B6 results and any supplementation with your doctor, especially if you take other medications.